Are Clinical Trials Dangerous?

Every clinical trial that takes place at a medical research facility, such as a hospital or university, must be reviewed and approved by a board of physicians, researchers, and community members. This helps ensure that the study is conducted fairly and that the participants aren't harmed.

However, clinical trials still involve some degree of risk for participants. Before making the decision to volunteer for a clinical trial, it is important to understand exactly what is involved in the study.

When looking at a clinical trial, two important things to consider are the chance of harm that is, the likelihood that particular side effects will occur and the degree of harm that is, the seriousness of potential side effects. In most cases, volunteers risk only minor, temporary discomfort. In some cases, though, more serious medical complications are possible.

Very rarely, volunteers have been seriously injured or died as a result of treatment received in a clinical trial. Every person who joins a clinical trial must first sign a consent document that explains the research study in clear language. He or she will also meet with a member of the research team, who will explain the study, the volunteer's role, and answer any questions.

Deciding whether to participate in a clinical trial is an important personal decision. Many find it helpful to discuss the study with friends, family, or a physician before choosing whether to participate. Study participants may choose to withdraw from a clinical at any time.