Paid Clinical Trials in Canada

Paid Clinical Trials and Focus Groups by Location

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Omega-3 Fatty Acid Supplementation in Children

Conditions: Chronic Kidney Disease; Hypertriglyceridemia
Interventions: Dietary Supplement: n-3 Fatty Acid supplement; Dietary Supplement: Placebo
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified March 2010
Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity

Condition: Colorectal Neoplasms
Interventions: Drug: Glutamine; Drug: Calcium and Magnesium
Sponsor: Sanofi-Aventis
Recruiting - verified March 2010
Safety and Efficacy of Linagliptin in Type-2-diabetes Mellitus Patients With Moderate to Severe Renal Impairment

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Linagliptin; Drug: Placebo; Drug: Glimepiride
Sponsor: Boehringer Ingelheim Pharmaceuticals
Recruiting - verified March 2010
The Effect of Recombinant Human Erythropoietin (rHuEPO) on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis and Septic Shock

Conditions: Sepsis; Shock
Intervention:
Sponsor: London Health Sciences Centre
Recruiting - verified December 2009
Response to SLT vs. ALT in Patients Under 60 Years of Age

Condition: Glaucoma
Interventions: Procedure: Argon laser trabeculoplasty; Procedure: Selective laser trabeculoplasty
Sponsor: Sunnybrook Health Sciences Centre
Completed - verified March 2010
Weaning And Variability Evaluation (WAVE)

Condition: Extubation
Intervention:
Sponsors: Ottawa Hospital Research Institute; The Physicians' Services Incorporated Foundation
Completed - verified March 2010
Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis

Condition: Primary Sclerosing Cholangitis
Intervention: Drug: ursodeoxycholic acid (UDCA) withdrawal and reinstitution
Sponsors: University of Tennessee; Mount Sinai School of Medicine; Children's Memorial Hospital; University of California, San Francisco; The Hospital for Sick Children; University of Colorado, Denver; Children's Hospital Medical Center, Cincinnati; University of Pittsburgh
Not yet recruiting - verified March 2010
Tomosynthesis in Screening Mammography

Condition: Breast Density ≥ 50%
Intervention: Procedure: tomosynthesis
Sponsors: Alberta Health Services; Hologic, Inc.
Not yet recruiting - verified March 2010
Objective Systolic Function Recuperation Assessed by Echocardiography

Conditions: Myocardial Infarction; Left Ventricular Systolic Dysfunction; Anterior Akinesis; Apical Akinesis
Intervention:
Sponsor: Universitaire de Sherbrooke
Not yet recruiting - verified March 2010
Peripartum Cardiomyopathy

Condition: Pregnant Women With Peripartum Cardiomyopathy
Intervention:
Sponsors: University of Pittsburgh; National Institutes of Health (NIH)
Recruiting - verified March 2010
Getting on With the Rest of Your Life After a Stroke

Condition: Stroke
Interventions: Other: Mission Possible; Other: delayed mission possible
Sponsors: McGill University; Canadian Stroke Network
Recruiting - verified September 2009
The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

Condition: Post-tetanic Count on One Arm, the Other Arm is the Control
Intervention: Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Sponsor: Maisonneuve-Rosemont Hospital
Recruiting - verified March 2010
Efficacy and Safety of Linagliptin in Elderly Patients With Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: linagliptin; Drug: placebo
Sponsor: Boehringer Ingelheim Pharmaceuticals
Recruiting - verified March 2010
Impact of Spices and Herbs on Endothelial Function

Condition: Endothelial Function
Interventions: Dietary Supplement: Cinnamon; Dietary Supplement: Oregano; Dietary Supplement: Ginger; Dietary Supplement: Rosemary; Dietary Supplement: Black pepper; Dietary Supplement: Placebo
Sponsors: Laval University; McCormick Canada Co
Recruiting - verified March 2010
EArly Discharge After Transradial Stenting of CoronarY Arteries in High-Risk Patients of Bleeding

Condition: Coronary Artery Disease
Interventions: Drug: Bivalirudin; Drug: Heparin
Sponsor: Laval University
Active, not recruiting - verified October 2009
Vaginal Microbiota Among Postmenopausal Women

Condition: Vulvovaginal Atrophy
Intervention:
Sponsors: Lawson Health Research Institute; Kimberly-Clark Corporation
Recruiting - verified March 2010
PeriOperative ISchemic Evaluation-2 Trial

Condition: Cardiovascular Disease
Interventions: Drug: Active Clonidine; Drug: Placebo Clonidine; Drug: Active ASA; Drug: Placebo ASA
Sponsor: Hamilton Health Sciences
Not yet recruiting - verified March 2010
Safety and Tolerability of Dabigatran Etexilate Solution in Children 1 to < 12 Years of Age

Condition: Venous Thromboembolism
Intervention: Drug: dabigatran etexilate
Sponsor: Boehringer Ingelheim Pharmaceuticals
Recruiting - verified March 2010
Calling for Care: Cell Phones for Mood Telemetry

Conditions: Bipolar Disorder; Cyclothymia; Borderline Personality Disorder
Intervention: Other: Mental health telemetry (MHT)
Sponsors: Sunnybrook Health Sciences Centre; Motorola Canada
Not yet recruiting - verified March 2010
Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension

Condition: Pulmonary Arterial Hypertension (Idiopathic, Familial or Anorexigen-associated)
Interventions: Drug: Dichloroacetate Sodium; Drug: Dichloroacetate Sodium; Drug: Dichloroacetate Sodium
Sponsors: University of Alberta; Imperial College London
Enrolling by invitation - verified March 2010
Development and Evaluation of a Nursing Virtual Intervention Tailored for Pain After Cardiac Surgery

Conditions: Cardiac Surgery; Pain; Adult; Pain Management
Intervention: Behavioral: soulageTAVIE
Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Canadian Institutes of Health Research (CIHR); GRISIIQ; FIIC; Chaire de recherche sur les nouvelles pratiques de soins infirmiers
Recruiting - verified February 2010
Randomized, Controlled Study of CF Patients Between 3 Months and Less Than 7 Years

Condition: Treatment of Early Pulmonary Infections With P. Aeruginosa in Cystic Fibrosis Patients
Interventions: Drug: TOBI; Drug: Placebo to TOBI
Sponsor: Novartis Pharmaceuticals
Recruiting - verified March 2010
Phase II Trial of AUY922 vs. Comparators in Advanced Gastric Cancer

Conditions: Advanced Gastric Cancer; Gastro-esophageal Junction Cancer
Interventions: Drug: AUY922; Drug: Docetaxel or Irinotecan
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - verified March 2010
Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children

Condition: Otitis Media With Effusion
Interventions: Drug: Lansoprazole; Drug: Placebo
Sponsors: Hamilton Health Sciences; McMaster University
Not yet recruiting - verified March 2010
Living With Hope Program for Rural Women Caregivers

Condition: Advanced Cancer
Intervention: Behavioral: Living with Hope Program
Sponsor: University of Saskatchewan
Recruiting - verified March 2010
Transcranial Magnetic Stimulation (TMS) in Parkinson's Disease

Conditions: Parkinson's Disease; Depression
Intervention: Device: Transcranial Magnetic Stimulator
Sponsors: Beth Israel Deaconess Medical Center; Michael J. Fox Foundation for Parkinson's Research
Not yet recruiting - verified March 2010
Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use NSAIDs and/or Colchicines.

Condition: Acute Gout
Interventions: Drug: ACZ885; Drug: Triamcinolone acetonide
Sponsor: Novartis Pharmaceuticals
Recruiting - verified March 2010
Alzheimer's Disease Neuroimaging Initiative Grand Opportunity

Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention:
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA); National Institutes of Health (NIH)
Not yet recruiting - verified March 2010
Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients

Condition: Hypertension
Intervention:
Sponsors: Abbott; McKesson Canada
Recruiting - verified February 2010
Emergency Department (ED)-Directed Interventions to Improve Asthma Guideline Compliance

Condition: Acute Asthma
Interventions: Behavioral: Opinion Leader; Behavioral: Usual care
Sponsor: University of Alberta
Not yet recruiting - verified February 2010
Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosis

Condition: Distal Subungual Onychomycosis
Interventions: Drug: Terbinafine Hydrochloride; Other: Purified Water
Sponsor: Nitric BioTherapeutics, Inc
Not yet recruiting - verified March 2010
Cost-Effectiveness of Web-Based Follow Ups

Conditions: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee
Interventions: Other: in-person; Other: web-based
Sponsors: University of Western Ontario, Canada; The Physicians' Services Incorporated Foundation
Recruiting - verified March 2010
The Effectiveness of Antibiotic Cement (ABC) Compared to Regular Cement in Reducing the Rate of Infection Following Total Knee Arthroplasty: The ABC Trial

Conditions: Infection; Osteoarthritis of the Knee
Interventions: Device: Simplex™ P with Tobramycin; Device: Simplex™ P
Sponsor: University of Western Ontario, Canada
Not yet recruiting - verified March 2010
Canadian Hemophilia Prophylaxis Study

Condition: Severe Hemophilia A
Interventions: Biological: Recombinant Factor VIII (Advate/Helixate FS/KoegenateFS); Biological: Recombinant Factor VIII (Advate/Helixate FS/KoegenateFS)
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified March 2010
Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Ovarian Cancer and Inoperable Malignant Bowel Obstruction

Conditions: Ovarian Cancer; Bowel Obstruction
Interventions: Drug: Cisplatin; Drug: Paclitaxel
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer

Condition: Ovarian Cancer
Interventions: Drug: olaparib; Drug: paclitaxel; Drug: carboplatin
Sponsor: AstraZeneca
Recruiting - verified March 2010
A Study Evaluating the Clinical Benefit of Adding Custirsen to Docetaxel Retreatment/Prednisone as Second Line Therapy in Men With Castrate Resistant Prostate Cancer (CRPC)

Conditions: Castrate-Resistant Prostate Cancer; Hormone Refractory Prostate Cancer
Interventions: Drug: custirsen sodium; Drug: Isotonic, 0.9% sodium chloride
Sponsors: OncoGenex Technologies; Teva Pharmaceuticals USA
Not yet recruiting - verified March 2010
Oxygen Saturation Patterns in Post-Op Patients at Risk for Obstructive Sleep Apnea

Condition: Obstructive Sleep Apnea
Intervention:
Sponsor: Covidien
Recruiting - verified February 2010
Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome

Condition: Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome
Intervention: Biological: Serostim
Sponsor: EMD Serono
Completed - verified March 2010
An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Condition: Familial Hypercholesterolaemia
Interventions: Drug: rosuvastatin calcium; Drug: rosuvastatin calcium; Drug: rosuvastatin calcium
Sponsor: AstraZeneca
Recruiting - verified March 2010
A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis Who Have Prior Exposure to Anti TNF Agents

Condition: Arthritis, Psoriatic
Interventions: Drug: ustekinumab; Drug: placebo; Drug: placebo; Drug: ustekinumab; Drug: ustekinumab; Drug: placebo; Drug: ustekinumab; Drug: ustekinumab
Sponsor: Centocor, Inc.
Not yet recruiting - verified February 2010
Eccentric Exercise Training as Novel Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD)

Conditions: Pulmonary Disease, Chronic Obstructive; Bronchitis, Chronic; Emphysema
Intervention: Other: Eccentric exercise training
Sponsors: McGill University; McGill University Health Center
Recruiting - verified December 2009
Screening DIVA - Diffuse Vascular Disease

Condition: Peripheral Vascular Diseases
Intervention:
Sponsors: Sanofi-Aventis; Bristol-Myers Squibb
Recruiting - verified February 2010
Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: NN1250; Drug: insulin glargine
Sponsor: Novo Nordisk
Recruiting - verified March 2010
nEw3 Post-approval Study

Conditions: Arrhythmia; Bradycardia
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
4965 Post-approval Study

Conditions: Arrhythmia; Heart Failure
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
4968 Post-approval Study

Conditions: Arrhythmia; Heart Failure
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
SB939 in Treating Patients With Recurrent or Metastatic Prostate Cancer

Condition: Prostate Cancer
Interventions: Drug: HDAC inhibitor SB939; Other: laboratory biomarker analysis
Sponsor: NCIC Clinical Trials Group
Recruiting - verified February 2010
Decision Making on Radioactive Iodine Treatment for Papillary Thyroid Cancer

Condition: Thyroid Cancer
Intervention: Other: Decision aid exposure
Sponsors: University Health Network, Toronto; Ontario Ministry of Health and Long Term Care; Canadian Institutes of Health Research (CIHR)
Recruiting - verified January 2010
A Study in Patients With Type 2 Diabetes Mellitus (AWARD-2)

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Insulin Glargine; Drug: LY2189265
Sponsor: Eli Lilly and Company
Recruiting - verified March 2010
Prevention of Weight Gain in Early Schizophrenia and Schizoaffective Disorder

Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Behavioral: Behavioural Intervention for the Prevention of Weight Gain
Sponsors: Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR)
Recruiting - verified March 2010
Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients

Condition: Knee Osteoarthritis
Interventions: Dietary Supplement: Glucosamine sulphate; Other: Placebo
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Intravenous Fluid for Pediatric Migraine in the Emergency Department

Conditions: Migraine; Headache; Pediatric
Intervention: Drug: Normal saline
Sponsor: University of Alberta
Not yet recruiting - verified February 2010
Neuroprotection and Repair in Optic Neuritis

Conditions: Multiple Sclerosis; Optic Neuritis; Minocycline
Intervention: Drug: Minocycline
Sponsors: University of Calgary; Neuroscience Canada
Recruiting - verified February 2010
The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery

Condition: Radiculopathy
Intervention: Drug: Kenalog and Sensorcaine
Sponsor: Saint John Regional Hospital
Not yet recruiting - verified January 2010
Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease

Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Placebo; Drug: Tiotropium
Sponsors: Boehringer Ingelheim Pharmaceuticals; Pfizer
Recruiting - verified March 2010
Indomethacin and Cardiac Bypass Surgery

Condition: Hemorrhage
Interventions: Drug: Indomethacin; Drug: Acetaminophen & Indomethacin; Drug: Acetaminophen
Sponsor: Queen's University
Completed - verified February 2010
Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use NSAIDs and/or Colchicine

Condition: Acute Gout
Interventions: Drug: ACZ885; Drug: Triamcinolone acetonide
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - verified February 2010
A Dose Ranging Study of AIN457 in Patients With Moderate to Severe Chronic Plaque-type Psoriasis

Condition: Chronic Plaque-type Psoriasis
Interventions: Drug: AIN457; Drug: Placebo
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - verified February 2010
Remote Ischemic Preconditioning in Cardiac Surgery Trial

Condition: Cardiac Surgery
Interventions: Procedure: Remote Ischemic Preconditioning; Procedure: Sham
Sponsors: Hamilton Health Sciences; Canadian Network and Centre for Trials Internationally
Not yet recruiting - verified January 2010
Onset of Labor and Metabolomics (GEM-2)

Condition: Pregnancy
Intervention:
Sponsor: Universitaire de Sherbrooke
Recruiting - verified February 2010
Pharmacokinetics of Oral Morphine and Pharmacogenomics of CYP2D6 and UGT2B7, in an Urban Pediatric Population Presenting for Elective Surgery

Condition: Pain
Interventions: Drug: Morphine; Drug: Morphine; Drug: Morphine
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Validation of Dyskinesia Rating Scales

Condition: Parkinson's Disease
Interventions: Drug: Amantadine; Drug: Placebo
Sponsors: Rush University Medical Center; Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified February 2010
Partial Thromboplastin Time During the First 24 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin (UFH)

Condition: Thrombosis
Interventions: Drug: Variation of heparin dose; Drug: Variation of heparin dose
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting - verified February 2010
Naloxone for the Treatment of Opioid-Induced Pruritus

Condition: Pruritus
Interventions: Drug: Naloxone; Drug: Saline/Morphine
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Study of Vidaza Versus Conventional Care Regimens for the Treatment of Acute Myeloid Leukemia (AML)

Condition: Acute Myeloid Leukemia
Interventions: Drug: A: Azacitidine (Vidaza); Drug: B: Conventional Care Regimen
Sponsor: Celgene Corporation
Not yet recruiting - verified February 2010
Fluid Lavage of Open Wounds (FLOW): Pilot Trial

Conditions: Infection; Wound Healing Problem; Nonunion
Interventions: Procedure: Type of fluid lavage solution; Procedure: Type of fluid lavage pressure
Sponsors: McMaster University; The Physicians' Services Incorporated Foundation; Orthopaedic Trauma Association
Completed - verified February 2010
The Electronic Asthma Action Plan System for Implementation in Primary Care

Condition: Asthma
Intervention: Other: Electronic Asthma Action Plan System
Sponsor: St. Michael's Hospital, Toronto
Not yet recruiting - verified February 2010
Assessment of the Impact of a Stepped Mouthpiece on the Upper Airways Measured Through Acoustic Pharyngometry

Condition: Obstructive Sleep Apnea
Intervention:
Sponsor: Doctor's Directive Strategies Inc.
Active, not recruiting - verified December 2009
Efficacy and Safety of Titrated Oral Misoprostol Solution for Labor Induction at Term

Condition: Labor Induction at Term
Intervention: Drug: Misoprostol
Sponsor: University of Manitoba
Not yet recruiting - verified February 2010

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