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Paid Clinical Trials in Germany

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  • Safety & Efficacy Study of the IRay System in Patients With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

    Conditions:   AMD;   Wet AMD;   Age-Related Macular Degeneration;   Wet Age-Related Macular Degeneration;   Macular Degeneration;   Eye Diseases;   Retinal Diseases
    Intervention:   Device: IRay
    Sponsor:   Oraya Therapeutics, Inc.
    Not yet recruiting - verified November 2009

  • Safety and Immune Response to Adjuvanted A(H1N1)v Influenza Vaccine in HIV-1 Infected and Immunosuppressed Adult Patients

    Conditions:   HIV-1 Infection;   Cancer;   Immunosuppression
    Intervention:   Other: serologic testing
    Sponsors:   Johann Wolfgang Goethe University;   HIVCENTER
    Recruiting - verified November 2009

  • Controlled Trial Comparing the Performance of 22G vs 25G EUS-FNA Needles (FNA-22G-25G)

    Conditions:   Mediastinal Tumours and Lymph Nodes;   Celiac, Perigastric and Peri-pancreatic Lymph Nodes;   Pancreatic Masses;   Liver Masses;   Adrenal Masses
    Intervention:  
    Sponsors:   University Hospital, Gentofte, Copenhagen;   University of Medicine and Pharmacy Craiova;   Allgemeines Krankenhaus Celle, Celle, Germany;   Pathologic Institute, Wittinger Strasse, Celle, Germany;   Sana Hospital Lübeck GmbH, Lübeck, Germany;   Hospital Grosshansdorf, Grosshandorf, Germany;   Medical University Schleswig-Holstein, Luebeck, Germany
    Recruiting - verified November 2009

  • Misago Iliac Study

    Condition:   Iliac Lesions
    Intervention:   Device: Misago (stent placement)
    Sponsor:   Flanders Medical Research Program
    Not yet recruiting - verified November 2009

  • Banded Versus Conventional Laparoscopic Roux-en-Y (GABY)

    Condition:   Morbid Obesity Requiring Bariatric Surgery
    Interventions:   Procedure: Conventional laparoscopic Roux-en-Y gastric bypass;   Procedure: conventional laparoscopic Roux-en-Y gastric bypass with additional restrictive silastic ring
    Sponsor:   ClinTrio Ltd.
    Recruiting - verified November 2009

  • A Study of CellCept (Mycophenolate Mofetil) in Lung Transplant Recipients

    Condition:   Lung Transplantation
    Intervention:   Drug: mycophenolate mofetil [CellCept]
    Sponsor:   Hoffmann-La Roche
    Not yet recruiting - verified November 2009

  • Intra-individual Comparison of the Efficacy of Two Botulinum Toxins Type A on Moderate to Severe Forehead Wrinkles After One Injection

    Condition:   Forehead Wrinkles
    Intervention:   Drug: botulinum toxin
    Sponsor:   Galderma
    Active, not recruiting - verified November 2009

  • Single-arm Study of Photodynamic Laser Therapy Using Foscan for Non-curatively-resectable Bile Duct Carcinoma

    Condition:   Non-curative Resectable Bile Duct Carcinoma
    Intervention:   Drug: Temoporfin
    Sponsors:   University of Salzburg;   Biolitec Pharma ltd., United Drug House, Magna Drive,Dublin 24,Irland
    Recruiting - verified November 2009

  • A Study of the Safety and Efficacy of 4 Doses of BI 1744 CL Delivered Via the Respimat in Patients With Asthma.

    Condition:   Asthma
    Interventions:   Drug: BI 1744 CL;   Drug: Placebo;   Drug: Respimat
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

    Conditions:   Brain Cancer;   Choroid Plexus Tumors
    Interventions:   Drug: Carboplatin;   Drug: Cisplatin;   Drug: Cyclophosphamide;   Drug: Dactinomycin;   Drug: Doxorubicin;   Drug: Etoposide;   Drug: Irinotecan;   Drug: Leucovorin;   Drug: Methotrexate;   Drug: Temozolomide;   Drug: Vincristine
    Sponsor:   M.D. Anderson Cancer Center
    Recruiting - verified November 2009

  • Efficacy and Safety of Candesartan Cilexetil Plus Hydrochlorothiazide in Subjects With Severe Hypertension

    Condition:   Hypertension
    Intervention:   Drug: Candesartan cilexetil and hydrochlorothiazide
    Sponsor:   Takeda Pharma GmbH
    Recruiting - verified November 2009

  • Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation

    Conditions:   QTc Evaluation;   Electrocardiography
    Interventions:   Drug: Avelox (Moxifloxacin, BAY12-8039);   Drug: Placebo
    Sponsor:   Bayer
    Not yet recruiting - verified November 2009

  • Cognitive Training to Improve Cognitive Function Following Chemotherapy

    Condition:   Cognitive Dysfunction
    Interventions:   Behavioral: cognitive training;   Other: control group
    Sponsors:   Charite University, Berlin, Germany;   Freie Universität Berlin
    Not yet recruiting - verified November 2009

  • Efficacy, Safety, Tolerability and Pharmacokinetics of Indacaterol Maleate Via Concept1 or Simoon Devices

    Condition:   Asthma
    Interventions:   Drug: QAB149 placebo;   Drug: QAB149;   Drug: QAB149;   Drug: QAB149
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Effect of Indacaterol on Inspiratory Capacity (IC)

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Indacaterol;   Drug: Tiotropium;   Drug: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Comparison of a PEG Membrane and a Collagen Membrane for the Treatment of Bone Dehiscence Defects at Bone Level Implants

    Condition:   Bone Dehiscence Defects
    Intervention:   Device: Implant surgery
    Sponsor:   Institut Straumann AG
    Recruiting - verified November 2009

  • Efficacy and Safety of Sublingual Immunotherapy (SLIT)

    Condition:   Allergic Rhinitis
    Interventions:   Biological: sublingual immunotherapy with allergen extract;   Biological: sublingual immunotherapy with placebo
    Sponsor:   Roxall Medizin
    Not yet recruiting - verified November 2009

  • A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen Extracts

    Conditions:   Allergic Rhinitis;   Allergic Conjunctivitis
    Interventions:   Biological: modified allergen extract;   Biological: Placebo
    Sponsor:   Roxall Medizin
    Not yet recruiting - verified November 2009

  • Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen

    Condition:   Allergic Rhinitis
    Interventions:   Biological: Subcutaneous injections with highly polymerized allergen extract;   Biological: Subcutaneous injection with placebo
    Sponsor:   Roxall Medizin
    Active, not recruiting - verified November 2009

  • Phase 3b Study to Evaluate Advagraf in Combination With Mycophenolate Mofetil and Basiliximab in Liver Transplantation

    Condition:   Liver Transplantation
    Interventions:   Drug: Advagraf;   Drug: Mycophenolate Mofetil;   Drug: Basiliximab;   Drug: Corticosteroids
    Sponsor:   Astellas Pharma Inc
    Recruiting - verified November 2009

  • An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys

    Condition:   Hepatitis B, Chronic
    Intervention:  
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen Rhinoconjunctivitis

    Condition:   Rhinoconjunctivitis
    Interventions:   Drug: Mutaflor;   Drug: Placebo
    Sponsor:   Charite University, Berlin, Germany
    Completed - verified November 2009

  • Utilisation of Angiox® in European Practice

    Conditions:   Stable Angina (SA);   NSTE-ACS (NSTEMI and UA);   Stemi (Ste-acs)
    Intervention:  
    Sponsor:   The Medicines Company
    Recruiting - verified November 2009

  • A Study to Investigate the Efficacy of LT-02 in Patients With Mesalazine Refractory Ulcerative Colitis

    Conditions:   Ulcerative Colitis;   Large Intestine;   Diarrhea;   Abdominal Pain
    Interventions:   Drug: LT-02;   Drug: placebo
    Sponsor:   Lipid Therapeutics GmbH
    Not yet recruiting - verified November 2009

  • Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents

    Condition:   Migraine
    Intervention:   Dietary Supplement: Migra 3
    Sponsor:   Complen Health GmbH
    Not yet recruiting - verified November 2009

  • A Study of RO5072759 With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia

    Condition:   Lymphocytic Leukemia, Chronic
    Interventions:   Drug: RO5072759;   Drug: rituximab;   Drug: chlorambucil
    Sponsors:   Hoffmann-La Roche;   Genentech
    Not yet recruiting - verified November 2009

  • International Active Surveillance Study - Safety of Contraceptives: Role of Estrogens

    Condition:   Contraception
    Intervention:  
    Sponsors:   Center for Epidemiology and Health Research, Germany;   Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
    Recruiting - verified November 2009

  • Pharmacodynamics, Safety and Pharmacokinetics of BMS-663068 in HIV-1

    Condition:   HIV-1 Infections
    Intervention:   Drug: BMS-663068 with or without ritonavir
    Sponsor:   Bristol-Myers Squibb
    Not yet recruiting - verified November 2009

  • Third-line Therapy of Multiple Myeloma a Prospective Phase I /II Trial

    Condition:   Multiple Myeloma
    Intervention:   Drug: Lenalidomide, Pioglitazone, dexamethasone, treosulfan
    Sponsors:   University of Regensburg;   ClinAssess GmbH
    Recruiting - verified November 2009

  • An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease

    Conditions:   Crohn's Disease;   Inflammatory Bowel Disease
    Intervention:   Drug: AIN457
    Sponsor:   Novartis Pharmaceuticals
    Enrolling by invitation - verified November 2009

  • Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: GSK239512;   Drug: Placebo
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009

  • The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery

    Conditions:   Stress Physiology;   Staff Work Load;   Artificial Pneumoperitoneum;   Anuria
    Intervention:   Behavioral: IPP
    Sponsors:   Hannover Medical School;   Dresden University of Technology;   University of Zurich
    Completed - verified November 2009

  • Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression

    Conditions:   Depressive Symptoms;   Diabetes Mellitus
    Interventions:   Behavioral: Diabetes-Specific Cognitive-Behavioral Group Sessions;   Behavioral: Educative Group Lesson and Discussion
    Sponsors:   Forschungsinstitut der Diabetes Akademie Mergentheim;   Deutsches Diabetes-Zentrum (German Diabetes-Center) Duesseldorf;   University of Gießen, Departement of Psychosomatics;   Koordinierungszentrum fuer Klinische Studien (KKS), University of Duesseldorf
    Not yet recruiting - verified November 2009

  • Clinical Study of OncoSorb® in Patients With Advanced Cancer Entities

    Condition:   Advanced Cancer Entities
    Intervention:   Procedure: Apheresis using the OncoSorb column
    Sponsors:   BioPheresis GmbH;   Dr. M. Koehler GmbH;   ARTIMED Medical Consulting GmbH
    Recruiting - verified November 2009

  • Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

    Condition:   Heart Failure
    Intervention:  
    Sponsor:   Cardiac Concepts, Inc.
    Recruiting - verified November 2009

  • A Pharmacokinetic/Pharmacodynamic Study of Intravenous and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis on Methotrexate

    Conditions:   Arthritis;   Rheumatoid Arthritis
    Interventions:   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Other: Placebo IV;   Other: Placebo SC
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009

  • Influence of Piribedil (Clarium®) on Vigilance and Cognitive Function in Patients With Parkinson's Disease Compared to Other Non-Ergot Dopamine Agonists

    Condition:   Idiopathic Parkinson's Disease
    Interventions:   Drug: piribedil;   Drug: pramipexole or ropinirole
    Sponsors:   Desitin Arzneimittel GmbH;   FGK Clinical Research GmbH
    Not yet recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Drug-Eluting Balloon Catheters and the Treatment of Peripheral Arterial Occlusive Disease

    Conditions:   Peripheral Arterial Disease;   Stenotic Femoro-popliteal Arteries;   Occluded Femoro-popliteal Arteries;   Atherosclerosis
    Intervention:   Other: Paclitaxel-coated balloon catheter angioplasty
    Sponsor:   MEDRAD Interventional/Possis
    Completed - verified November 2009

  • Randomized, Placebo Controlled, Cross-over Study in the Enviromental Challenge Chamber to Assess Safety & Efficiacy of Three Oral Doses of BI 671800 Versus Fluticason Propionate and Montelukast in Sensitive Seasonal Allergic Rhintis Patients Out of Season

    Conditions:   Rhinitis, Allergic, Seasonal;   Asthma
    Interventions:   Drug: BI 671800 ED;   Drug: Fluticasone Propionate Nasal Spray;   Drug: Montelukast 10 mg
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Feasibility and Safety of NeuroFlo in Stroke Patients Receiving Tissue Plasminogen Activator (tPA)

    Condition:   Ischemic Stroke
    Intervention:   Device: NeuroFlo catheter
    Sponsor:   CoAxia
    Active, not recruiting - verified November 2009

  • Sugammadex and Neostigmine at Residual Neuromuscular Blockade

    Condition:   Residual Neuromuscular Block (TOF-ratio of 0.2)
    Interventions:   Drug: Sugammadex;   Drug: Neostigmine;   Drug: Saline
    Sponsor:   Technische Universität München
    Recruiting - verified September 2009

  • Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)

    Condition:   Retinal Vein Occlusion
    Interventions:   Drug: VEGF Trap-Eye (BAY86-5321);   Other: Sham treatment
    Sponsors:   Bayer;   Regeneron Pharmaceuticals
    Recruiting - verified November 2009

  • Weight Approximation in Stroke Before Thrombolysis

    Condition:   Stroke
    Intervention:   Other: Recording of body weight estimations, approximations and tPA dose
    Sponsor:   University of Erlangen-Nürnberg
    Not yet recruiting - verified November 2009

  • Lapatinib in Combination With Vinorelbine

    Conditions:   Cancer;   Neoplasms, Breast
    Interventions:   Drug: Lapatinib;   Drug: Vinorelbine;   Drug: Capecitabine
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009

  • Safety and Efficacy Study of Kaname Coronary Stent System for the Treatment of Patients With Coronary Artery Disease

    Conditions:   Coronary Artery Disease;   Angioplasty, Transluminal, Percutaneous Coronary
    Intervention:   Device: Kaname cobalt-chromium coronary stent
    Sponsor:   Terumo Europe N.V.
    Not yet recruiting - verified October 2009

  • Effects of Low Versus High Carbohydrate Diet During Rehabilitation on Cardiovascular Function and Metabolism in Type 2 Diabetes

    Conditions:   Type 2 Diabetes Mellitus;   Overweight
    Interventions:   Other: LOGI diet;   Other: Low Fat diet
    Sponsors:   Munich Municipal Hospital;   Stately Pension System (LVA) Baden-Wuertemberg;   Ueberruh Rehabilitation Clinic, Isny, Baden-Wuertemberg
    Active, not recruiting - verified October 2009

  • A Study of Pemetrexed and Bevacizumab for Patients With Advanced Non Small Cell Cancer

    Condition:   Non Small Cell Lung Cancer
    Interventions:   Drug: Pemetrexed;   Drug: Cisplatin;   Drug: Bevacizumab
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Phase IIa Study of MP4OX in Hemorrhagic Shock Patients With Lactic Acidosis

    Conditions:   Shock, Hemorrhagic;   Shock, Traumatic;   Acidosis, Lactic
    Interventions:   Drug: MP4OX;   Drug: MP4OX;   Drug: Ringer's Lactate solution
    Sponsor:   Sangart
    Not yet recruiting - verified November 2009

  • Comparison of CNAP With Invasive Arterial Pressure Monitoring

    Condition:   Blood Pressure
    Intervention:  
    Sponsor:   University of Schleswig-Holstein
    Recruiting - verified October 2009

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