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Paid Clinical Trials in Germany

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  • An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease

    Conditions:   Crohn's Disease;   Inflammatory Bowel Disease
    Intervention:   Drug: AIN457
    Sponsor:   Novartis Pharmaceuticals
    Enrolling by invitation - verified November 2009

  • Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression

    Conditions:   Depressive Symptoms;   Diabetes Mellitus
    Interventions:   Behavioral: Diabetes-Specific Cognitive-Behavioral Group Sessions;   Behavioral: Educative Group Lesson and Discussion
    Sponsors:   Forschungsinstitut der Diabetes Akademie Mergentheim;   Deutsches Diabetes-Zentrum (German Diabetes-Center) Duesseldorf;   University of Gießen, Departement of Psychosomatics
    Not yet recruiting - verified November 2009

  • The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery

    Conditions:   Stress Physiology;   Staff Work Load;   Artificial Pneumoperitoneum;   Anuria
    Intervention:   Behavioral: IPP
    Sponsors:   Hannover Medical School;   Dresden University of Technology;   University of Zurich
    Completed - verified November 2009

  • Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: GSK239512;   Drug: Placebo
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009

  • Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

    Condition:   Heart Failure
    Intervention:  
    Sponsor:   Cardiac Concepts, Inc.
    Recruiting - verified November 2009

  • A Pharmacokinetic/Pharmacodynamic Study of Intravenous and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis on Methotrexate

    Conditions:   Arthritis;   Rheumatoid Arthritis
    Interventions:   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Other: Placebo IV;   Other: Placebo SC
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Influence of Piribedil (Clarium®) on Vigilance and Cognitive Function in Patients With Parkinson's Disease Compared to Other Non-Ergot Dopamine Agonists

    Condition:   Idiopathic Parkinson's Disease
    Interventions:   Drug: piribedil;   Drug: pramipexole or ropinirole
    Sponsors:   Desitin Arzneimittel GmbH;   FGK Clinical Research GmbH
    Not yet recruiting - verified November 2009

  • Randomized, Placebo Controlled, Cross-over Study in the Enviromental Challenge Chamber to Assess Safety & Efficiacy of Three Oral Doses of BI 671800 Versus Fluticason Propionate and Montelukast in Sensitive Seasonal Allergic Rhintis Patients Out of Season

    Conditions:   Rhinitis, Allergic, Seasonal;   Asthma
    Interventions:   Drug: BI 671800 ED;   Drug: Fluticasone Propionate Nasal Spray;   Drug: Montelukast 10 mg
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Drug-Eluting Balloon Catheters and the Treatment of Peripheral Arterial Occlusive Disease

    Conditions:   Peripheral Arterial Disease;   Stenotic Femoro-popliteal Arteries;   Occluded Femoro-popliteal Arteries;   Atherosclerosis
    Intervention:   Other: Paclitaxel-coated balloon catheter angioplasty
    Sponsor:   MEDRAD Interventional/Possis
    Completed - verified November 2009

  • Feasibility and Safety of NeuroFlo in Stroke Patients Receiving Tissue Plasminogen Activator (tPA)

    Condition:   Ischemic Stroke
    Intervention:   Device: NeuroFlo catheter
    Sponsor:   CoAxia
    Active, not recruiting - verified November 2009

  • Sugammadex and Neostigmine at Residual Neuromuscular Blockade

    Condition:   Residual Neuromuscular Block (TOF-ratio of 0.2)
    Interventions:   Drug: Sugammadex;   Drug: Neostigmine;   Drug: Saline
    Sponsor:   Technische Universität München
    Recruiting - verified September 2009

  • Weight Approximation in Stroke Before Thrombolysis

    Condition:   Stroke
    Intervention:   Other: Recording of body weight estimations, approximations and tPA dose
    Sponsor:   University of Erlangen-Nürnberg
    Not yet recruiting - verified November 2009

  • Safety and Efficacy Study of Kaname Coronary Stent System for the Treatment of Patients With Coronary Artery Disease

    Conditions:   Coronary Artery Disease;   Angioplasty, Transluminal, Percutaneous Coronary
    Intervention:   Device: Kaname cobalt-chromium coronary stent
    Sponsor:   Terumo Europe N.V.
    Not yet recruiting - verified October 2009

  • Effects of Low Versus High Carbohydrate Diet During Rehabilitation on Cardiovascular Function and Metabolism in Type 2 Diabetes

    Conditions:   Type 2 Diabetes Mellitus;   Overweight
    Interventions:   Other: LOGI diet;   Other: Low Fat diet
    Sponsors:   Munich Municipal Hospital;   Stately Pension System (LVA) Baden-Wuertemberg;   Ueberruh Rehabilitation Clinic, Isny, Baden-Wuertemberg
    Active, not recruiting - verified October 2009

  • A Study of Pemetrexed and Bevacizumab for Patients With Advanced Non Small Cell Cancer

    Condition:   Non Small Cell Lung Cancer
    Interventions:   Drug: Pemetrexed;   Drug: Cisplatin;   Drug: Bevacizumab
    Sponsor:   Eli Lilly and Company
    Recruiting - verified October 2009

  • Phase IIa Study of MP4OX in Hemorrhagic Shock Patients With Lactic Acidosis

    Conditions:   Shock, Hemorrhagic;   Shock, Traumatic;   Acidosis, Lactic
    Interventions:   Drug: MP4OX;   Drug: MP4OX;   Drug: Ringer's Lactate solution
    Sponsor:   Sangart
    Not yet recruiting - verified October 2009

  • Comparison of CNAP With Invasive Arterial Pressure Monitoring

    Condition:   Blood Pressure
    Intervention:  
    Sponsor:   University of Schleswig-Holstein
    Recruiting - verified October 2009

  • Routine Bile Collection for Microbiological Analysis During Cholangiography

    Condition:   Cholangitis
    Intervention:  
    Sponsors:   Hannover Medical School;   Integrated Research and Treatment Center-Transplantation
    Completed - verified October 2009

  • Evaluation of Radiesse® Injectable Dermal Filler for Hand Rejuvenation

    Condition:   Aging Hands
    Interventions:   Device: Radiesse® Injectable Dermal Filler;   Device: No Treatment
    Sponsor:   BioForm Medical, Inc.
    Active, not recruiting - verified October 2009

  • Study to Evaluate 13 C Isotope Ratio Measurement for Urea Cycle Capacity Assessment

    Condition:   Urea Cycle Disorders
    Intervention:   Other: sodium [1-13C] acetate
    Sponsor:   Cytonet GmbH & Co. KG
    Recruiting - verified October 2009

  • Quantification of Cerebral Cholinergic Function in Parkinson´s Disease by Means of Nuclear Medicine Methods

    Conditions:   Parkinson´s Disease;   Acetylcholine;   SPECT
    Intervention:  
    Sponsor:   Saarland University
    Not yet recruiting - verified October 2009

  • Treatment With Lenalidomide, Bendamustine and Prednisone (RBP) in Patients With Relapsed or Refractory Multiple Myeloma

    Condition:   Multiple Myeloma
    Intervention:   Drug: Lenalidomide, Bendamustine, Prednisone
    Sponsors:   University of Leipzig;   Celgene Corporation;   Mundipharma K.K.;   Amgen
    Recruiting - verified October 2009

  • Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma

    Condition:   Osteosarcoma
    Intervention:   Radiation: heavy ion radiotherapy (C12)
    Sponsors:   University of Heidelberg;   Dietmar Hopp Stiftung
    Not yet recruiting - verified October 2009

  • Efficacy and Safety of Aclidinium Bromide at Two Dose Levels Versus Placebo Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Aclidinium bromide;   Drug: Placebo
    Sponsors:   Almirall S.A.;   Forest Laboratories
    Recruiting - verified November 2009

  • 3-D Visualization of the Anti-Obstructive Effect of Levocetirizine

    Condition:   Allergic Rhinitis
    Intervention:   Drug: Levocetirizine
    Sponsor:   Clinical Research International Limited
    Not yet recruiting - verified October 2009

  • PDS*Plus and Wound Infections After Laparotomy

    Conditions:   Wound Infection;   Incisional Hernia
    Interventions:   Device: PDS plus;   Device: PDS II
    Sponsor:   University Hospital, Saarland
    Recruiting - verified October 2009

  • Study to Assess VB-201 in Patients With Psoriasis

    Condition:   Active Plaque Psoriasis
    Interventions:   Drug: VB-201;   Drug: VB-201;   Other: Placebo
    Sponsor:   Vascular Biogenics, Ltd
    Not yet recruiting - verified October 2009

  • A Study to Determine the Pharmacokinetics, Pharmacodynamics, and Tolerabiltiy of Betrixaban in Patients With Mild, Moderate, and Severe Renal Impairment

    Condition:   Renal Impairment
    Intervention:   Drug: Betrixaban
    Sponsors:   Portola Pharmaceuticals;   Merck
    Recruiting - verified October 2009

  • Ophthalmologic Examinations After Infusion of ZK200775

    Condition:   Visual Acuity
    Interventions:   Drug: ZK200775;   Drug: ZK200775;   Drug: Sodium Chloride
    Sponsors:   Charite University, Berlin, Germany;   Bayer Schering Pharma AG, Müllerstraße 178, 13353 Berlin
    Completed - verified October 2009

  • Arrested Versus Beating Heart Techniques in Coronary Revascularisation

    Condition:   Coronary Artery Bypass Grafting
    Interventions:   Procedure: Conventional Coronary Artery Bypass;   Procedure: Off-Pump Coronary Artery Bypass;   Procedure: Pump-Assisted Coronary Artery Bypass
    Sponsors:   Martin-Luther-Universität Halle-Wittenberg;   Medtronic
    Active, not recruiting - verified October 2009

  • Effect of Bromocriptine on Left Ventricular Function in Women With Peripartum Cardiomyopathy

    Condition:   Peripartum Cardiomyopathy
    Intervention:   Drug: Bromocriptine
    Sponsors:   Hannover Medical School;   BMBF (Bundes Ministerium für Bildung und Forschung);   ZKS Leipzig - KKS (Clinical Trial Centre Leipzig)
    Not yet recruiting - verified October 2009

  • Modified Ultrafiltration in Cardiac Surgery

    Conditions:   Coagulopathy;   Rethoracotomy;   Blood Loss;   Transfusion Requirements
    Intervention:   Device: modified ultrafiltration using Maquet haemoconcentrator, BC 20 plus
    Sponsor:   Johann Wolfgang Goethe University
    Recruiting - verified October 2009

  • EMD 525797 in Combination With Cetuximab and Irinotecan in K-ras Wildtype Metastatic Colorectal Cancer

    Condition:   Metastastic Colorectal Cancer
    Interventions:   Biological: EMD 525797, Irinotecan and Cetuximab;   Biological: EMD 525797, Irinotecan and Cetuximab;   Drug: Irinotecan and Cetuximab
    Sponsor:   EMD Serono
    Recruiting - verified November 2009

  • Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)

    Condition:   Rectal Cancer
    Interventions:   Procedure: side-to-end anastomosis;   Procedure: colon j pouch
    Sponsors:   Charite University, Berlin, Germany;   ChirNet
    Not yet recruiting - verified November 2009

  • Conventional Versus Point-of-care Based Coagulation Management

    Conditions:   Cardiac Surgery;   Coagulation Management
    Intervention:   Procedure: Point-of-Care versus conventional coagulation management
    Sponsors:   Johann Wolfgang Goethe University;   University Hospital, Essen
    Recruiting - verified October 2009

  • Epidemiological and Scientific Evaluation of EGFR Mutation Status in Patients With Newly Diagnosed Locally Advanced or Metastatic NSCLC

    Condition:   Newly Diagnosed Locally Advanced or Metastatic NSCLC
    Intervention:  
    Sponsor:   AstraZeneca
    Recruiting - verified October 2009

  • Study to Investigate Effects of a Herbal Drug Compared to Placebo on Sleep

    Conditions:   Healthy;   Sleep Quality
    Interventions:   Drug: Neurapas® balance (Herbal product (Hypericum, Passionflower, Valerian));   Drug: film-coated sugar-pill
    Sponsor:   Pascoe Pharmazeutische Preparate GmbH
    Completed - verified October 2009

  • Patterns of Non-Adherence to Dual Anti-Platelet Regimen In Stented Patients

    Conditions:   Medication Non-adherence;   Stent Thrombosis
    Intervention:  
    Sponsors:   Columbia University;   Bristol-Myers Squibb;   Sanofi-Aventis
    Recruiting - verified October 2009

  • Study of the Antidepressant Efficacy of a Combination Herbal Drug Preparation (NEURAPAS Balance)

    Condition:   Depressive Disorder
    Interventions:   Drug: Neurapas® balance (Herbal combination out of hypericum, valerian, passionflower);   Drug: film-coated sugar-pill
    Sponsor:   Pascoe Pharmazeutische Preparate GmbH
    Terminated - verified October 2009

  • EASSI - Evaluation of the Safety of Self-Administration With Icatibant

    Condition:   Hereditary Angioedema
    Intervention:   Drug: Icatibant
    Sponsor:   Jerini AG
    Recruiting - verified October 2009

  • Effects of Dietary Interventions on the Aging Brain

    Condition:   Healthy
    Interventions:   Behavioral: Caloric restriction;   Dietary Supplement: Omega-3 (fish oil capsules);   Dietary Supplement: Placebo
    Sponsor:   University Hospital Muenster
    Not yet recruiting - verified October 2009

  • Unilateral Versus Bilateral Endoscopic Lung Volume Reduction A Comparative Case Study

    Condition:   Pulmonary Emphysema
    Interventions:   Device: IBV Implantation;   Device: IBV Implantation
    Sponsors:   University of Heidelberg;   Spiration, Inc.
    Recruiting - verified October 2009

  • Randomized Study Comparing Two Established Gastrointestinal Suture Techniques - One-layer-continuous Versus Double-layer-continuous Suture

    Conditions:   Colo-colonic Anastomoses;   Ileo-colonic Anastomoses
    Interventions:   Procedure: double layer-suture;   Procedure: Single-layer suture
    Sponsor:   University Hospital Mannheim
    Recruiting - verified October 2009

  • Study Evaluating Safety, Tolerability and Efficacy of YM150 in Subjects With Acute Coronary Syndromes

    Condition:   Acute Coronary Syndrome
    Interventions:   Drug: YM150;   Drug: Placebo
    Sponsor:   Astellas Pharma Inc
    Recruiting - verified October 2009

  • Safety and Efficacy of AIN457 in Behçet's Patients With Posterior or Panuveitis

    Condition:   Behcet Disease
    Interventions:   Biological: AIN457;   Biological: AIN457;   Biological: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified October 2009

  • Long-Term Safety and Tolerability of Idebenone in Friedreich's Ataxia Patients (MICONOS Extension)

    Condition:   Freidreich's Ataxia
    Intervention:   Drug: idebenone
    Sponsor:   Santhera Pharmaceuticals
    Enrolling by invitation - verified October 2009

  • Qigong and Exercise Therapy for Low Back Pain in Adults

    Condition:   Low Back Pain
    Interventions:   Procedure: qigong;   Procedure: exercise therapy
    Sponsor:   Charite University, Berlin, Germany
    Not yet recruiting - verified October 2009

  • Comparison of Outcome Parameters in Laser Rhytide Treatment

    Condition:   Skin Aging
    Interventions:   Procedure: Fractional carbon dioxide laser treatment;   Procedure: Fractional Er:YAG laser treatment
    Sponsor:   Laserklinik Karlsruhe
    Completed - verified October 2009

  • Patient Satisfaction in Stroke Patients

    Condition:   Stroke
    Intervention:  
    Sponsors:   Charite University, Berlin, Germany;   Center for Stroke Research Berlin;   German Federal Ministry of Education and Research
    Recruiting - verified October 2009

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