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European Ambulance Acute Coronary Syndrome (ACS) Angiography Trial

Condition: ST Segment Elevation Acute Coronary Syndrome
Interventions: Drug: Bivalirudin; Drug: Heparin
Sponsor: The Medicines Company
Recruiting - verified March 2010
Armolipid Plus and Metabolic Syndrome

Condition: Metabolic Syndrome
Intervention: Dietary Supplement: Armolipid Plus
Sponsors: Rottapharm; Federico II University
Recruiting - verified March 2010
Treatment of Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Condition: LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Interventions: Other: RTX + CDDP/5-FU; Other: NO INDUCTION CHT + ( RTX + CETUXIMAB); Other: INDUCTION CHT + ( RTX + CDDP/5-FU); Other: INDUCTION CHT + ( RTX +CETUXIMAB)
Sponsors: Associazione Volontari Pazienti Oncologici; Mario Negri Institute for Pharmacological Research
Recruiting - verified March 2010
Diagnosis of Intestinal Motility by Image Analysis Using Capsule Endoscopy

Condition: Intestinal Abnormalities
Intervention: Device: PillCam SB2
Sponsor: Given Imaging Ltd.
Recruiting - verified March 2010
Balloon Elution and Late Loss Optimization (BELLO) Study

Condition: Coronary Artery Disease
Interventions: Device: IN.PACT Falcon paclitaxel eluting balloon (Drug eluting balloon); Device: Taxus (Paclitaxel eluting stent)
Sponsor: Fondazione Mediolanum per Attività e Ricerche Cardiovascolari Onlus
Not yet recruiting - verified March 2010
PeriOperative ISchemic Evaluation-2 Trial

Condition: Cardiovascular Disease
Interventions: Drug: Active Clonidine; Drug: Placebo Clonidine; Drug: Active ASA; Drug: Placebo ASA
Sponsor: Hamilton Health Sciences
Not yet recruiting - verified March 2010
Phase II Trial of AUY922 vs. Comparators in Advanced Gastric Cancer

Conditions: Advanced Gastric Cancer; Gastro-esophageal Junction Cancer
Interventions: Drug: AUY922; Drug: Docetaxel or Irinotecan
Sponsor: Novartis Pharmaceuticals
Not yet recruiting - verified March 2010
MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)

Condition: Metastatic Colorectal Cancer
Interventions: Drug: Mek Inhibitor MSC1936369B; Drug: Mek Inhibitor MSC1936369B; Drug: Placebo; Drug: FOLFIRI
Sponsor: EMD Serono
Recruiting - verified March 2010
The Effectiveness of the LCP in Improving End of Life Care for Dying Cancer Patients in Hospital.

Condition: Cancer Dying Patients
Intervention: Other: The LCP-I Program
Sponsor: Regional Palliative Care Network
Recruiting - verified March 2010
Effects of N-acetylcysteine on Diabetic Foot Oxygenation

Condition: Foot Ulcer, Diabetic
Intervention: Drug: N-acetylcysteine
Sponsor: University of Turin, Italy
Completed - verified February 2010
Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity

Condition: Retinopathy of Prematurity
Intervention: Drug: Propranolol
Sponsors: Azienda Ospedaliero, Universitaria Meyer; Ospedale Maggiore Policlinico Mangiagalli e Regina Elena
Recruiting - verified February 2010
A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies

Condition: Haematological Malignancies
Interventions: Drug: AS703569; Drug: AS703569
Sponsor: EMD Serono
Active, not recruiting - verified March 2010
Total Lymphoid Irradiation and Anti-Thymocyte Globulin in the Allogeneic Hematopoietic Cell Transplantation

Condition: Hematologic Malignancies
Intervention: Other: TOTAL LYMPHOID IRRADIATION
Sponsor: Fondazione Neoplasie Sangue Onlus
Recruiting - verified March 2010
Clinical Study to Evaluate Antibody and Cell Mediated Immunity of A/H1N1 Influenza Vaccine in Healthy Subjects

Condition: Influenza
Intervention: Biological: egg-derived A/H1N1 pandemic influenza vaccine
Sponsor: Opera Srl
Recruiting - verified March 2010
Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer

Condition: Ovarian Cancer
Interventions: Drug: olaparib; Drug: paclitaxel; Drug: carboplatin
Sponsor: AstraZeneca
Recruiting - verified March 2010
Pilot Study of Irreversible Electroporation (IRE) to Treat Early-Stage Primary Liver Cancer (HCC)

Condition: Carcinoma, Hepatocellular
Intervention: Device: Ablation with the NanoKnife Irreversible Electroporation (IRE) System
Sponsor: Angiodynamics, Inc.
Recruiting - verified March 2010
Safety Extension Study to Evaluate the Biodegradation of the Brimonidine Tartrate Posterior Segment Drug Delivery System

Condition: Patients Who Participated in an Intravitreal Brimo PS DDS® Study
Intervention: Drug: intravitreal brimonidine tartrate implant using Posterior Segment Drug Delivery System (PS DDS®) Applicator
Sponsor: Allergan
Recruiting - verified February 2010
Comparative Trial in Hormone Withdrawal Associated Symptoms

Condition: Hormone Withdrawal Associated Symptoms
Interventions: Drug: EE20/DRSP (YAZ, BAY86-5300); Drug: Ethinylestradiol (EE) and desogestrel (DSG) (Mercilon)
Sponsor: Bayer
Not yet recruiting - verified February 2010
A Pilot Trial of Interferon Beta-1a in Alzheimer's Disease

Condition: Alzheimer's Disease
Interventions: Drug: Interferon beta-1a; Drug: Placebo
Sponsor: Merck KGaA
Completed - verified March 2010
4965 Post-approval Study

Conditions: Arrhythmia; Heart Failure
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
nEw3 Post-approval Study

Conditions: Arrhythmia; Bradycardia
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
4968 Post-approval Study

Conditions: Arrhythmia; Heart Failure
Intervention:
Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting - verified February 2010
Retrospective Palivizumab Study in Children With Hemodynamically Significant Congenital Heart Disease

Condition: Severe Respiratory Syncytial Virus Infection
Intervention:
Sponsor: Abbott
Completed - verified February 2010
Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer

Condition: Thyroid Cancer
Intervention:
Sponsor: National Cancer Institute, Naples
Recruiting - verified February 2010
CoreValve Advance International Post Market Study

Condition: Severe Aortic Valve Stenosis
Intervention: Device: Medtronic CoreValve System
Sponsor: Medtronic Bakken Research Center
Recruiting - verified March 2010
Actions Elicited by In-hospital Follow-up of Cardiac Devices

Conditions: Pacemaker, Artificial; Defibrillators, Implantable
Intervention: Procedure: In-hospital follow-up of cardiac device
Sponsor: Cliniche Humanitas Gavazzeni
Recruiting - verified February 2010
Comparison of NN1250 Plus Insulin Aspart With Insulin Detemir Plus Insulin Aspart in Type 1 Diabetes

Condition: Diabetes Mellitus, Type 1
Interventions: Drug: NN1250; Drug: insulin detemir (Levemir®); Drug: insulin aspart
Sponsor: Novo Nordisk
Recruiting - verified March 2010
Study to Evaluate if the Addition of r-hLH (Luveris®) to FSH From Day 8 of Ovarian Stimulation is Able to Decrease Total FSH Dose and to Improve Cycle Outcome in Infertile Women Undergoing ART, Who Required High FSH Dose in a Previous Cycle

Condition: Reproductive Techniques, Assisted
Interventions: Drug: r-hFSH and r-hLH; Drug: r-hFSH
Sponsor: Merck KGaA
Terminated - verified July 2004
A Study of a New Candidate Vaccine Against Hepatitis C Virus (HCV)

Condition: Hepatitis C
Interventions: Biological: Ad6NSmut; AdCh3NSmut; Biological: Ad6NSmut; AdCh3NSmut; Biological: Ad6NSmut; AdCh3NSmut; Biological: Ad6NSmut; AdCh3NSmut; Biological: AdCh3NSmut; Ad6NSmut; Biological: AdCh3NSmut; Ad6NSmut; Biological: AdCh3NSmut; Ad6NSmut; Biological: AdCh3NSmut; Ad6NSmut; Biological: Ad6NSmut; AdCh3NSmut; Biological: AdCh3NSmut; Ad6NSmut; Biological: AdCh3NSmut; Ad6NSmut
Sponsors: Okairos; University of Oxford
Recruiting - verified February 2010
Inflammatory Effects of a Lung Recruitment Manoeuvre

Conditions: Respiratory Insufficiency; Respiratory Distress Syndrome, Adult
Interventions: Procedure: 40/30 recruitment manoeuvre; Device: continuous positive airway pressure (CPAP)
Sponsor: Azienda Ospedaliero, Universitaria Pisana
Not yet recruiting - verified February 2010
A Prospective Registry for Febrile Events in Patients With Malignant Hemopathies or Subjected to Haematopoietic Stem Cell Transplant

Conditions: Hematological Malignancies; Stem Cell Transplantation
Intervention:
Sponsors: Catholic University of the Sacred Heart; Pagano L, Aversa F, Locatelli F, Nosari A,Rossi G, Viale P
Completed - verified April 2009
Placebo Versus SBR759 in Lowering Phosphate in Dialysis Patients

Conditions: Hyperphosphatemia; Chronic Kidney Disease
Interventions: Drug: SBR759A; Drug: SBR759A; Drug: SBR759A; Drug: SBR759A; Drug: SBR759A
Sponsor: Novartis
Not yet recruiting - verified February 2010
Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

Condition: Intra-abdominal Infection
Interventions: Drug: Moxifloxacin (Avelox, BAY12-8039); Drug: Ertapenem, Amoxicillin/clavulanate
Sponsor: Bayer
Not yet recruiting - verified March 2010

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