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Paid Clinical Trials in the United Kingdom

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Paid Clinical Trials in United Kingdom

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  • A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Pulmonary Disease, Chronic Obstructive
    Interventions:   Drug: GW642444 Inhalation Powder;   Drug: FF/GW642444 Inhalation Powder
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Study of Ataluren (PTC124®) in Nonambulatory Patients With Nonsense-Mutation-Mediated Duchenne/Becker Muscular Dystrophy (nmDMD/BMD)

    Conditions:   Duchenne Muscular Dystrophy;   Becker Muscular Dystrophy
    Intervention:   Drug: Ataluren (PTC124)
    Sponsors:   PTC Therapeutics;   Genzyme
    Not yet recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)

    Condition:   Macular Degeneration
    Interventions:   Device: Epimacular Brachytherapy;   Drug: Ranibizumab
    Sponsors:   King's College Hospital NHS Trust;   NeoVista
    Not yet recruiting - verified November 2009

  • Multifunctional Magnetic Resonance (MR) for Radiotherapy Planning in Prostate Cancer

    Condition:   Prostate Cancer
    Interventions:   Other: Imaging Investigations (not radiation);   Other: Other
    Sponsors:   Royal Marsden NHS Foundation Trust;   Institute of Cancer Research, United Kingdom
    Recruiting - verified November 2009

  • Rehabilitation of Early Stroke Patients Using an AFO: an RCT

    Conditions:   Stroke;   Hemiplegia
    Intervention:   Other: Solid Ankle Foot Orthosis
    Sponsor:   University of Strathclyde
    Not yet recruiting - verified November 2009

  • Patient Satisfaction in the Critical Care Unit: A Qualitative Phenomenological Study

    Condition:   Patient Satisfaction in the Critical Care Unit
    Intervention:  
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified November 2009

  • Adherence to Self-care Regimens for Young People With Food Allergy

    Condition:   Food Allergy
    Intervention:  
    Sponsors:   Brighton & Sussex Medical School;   Brighton and Sussex University Hospitals NHS Trust;   Guys & St Thomas' Foundation NHS Trust
    Not yet recruiting - verified October 2009

  • Comparison of NN1250 With Insulin Glargine in Type 2 Diabetes

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: NN1250;   Drug: NN1250;   Drug: insulin glargine
    Sponsor:   Novo Nordisk
    Not yet recruiting - verified September 2009

  • CD64 Measurement in Neonatal Infection and Necrotising Enterocolitis

    Conditions:   Neonatal Sepsis;   Enterocolitis, Necrotizing
    Intervention:  
    Sponsor:   Newcastle-upon-Tyne Hospitals NHS Trust
    Recruiting - verified October 2009

  • Open-Label Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) Following a Single Oral Dose of AZD1236 in Healthy Male Subjects

    Condition:   Healthy
    Intervention:   Drug: 14C-AZD1236
    Sponsor:   AstraZeneca
    Recruiting - verified November 2009

  • Micronutrient Supplementation in Patients With Heart Failure

    Condition:   Heart Failure
    Interventions:   Drug: Placebo;   Drug: Forceval plus 50 micrograms Vitamin D3
    Sponsor:   Belfast Health and Social Care Trust
    Recruiting - verified October 2009

  • A Study of Routine Versus Selective Use of Ultrasound Scanning Prior to Haemodialysis Fistula Surgery

    Conditions:   Haemodialysis;   Surgery
    Intervention:   Procedure: Arterial and venous duplex ultrasound examination
    Sponsor:   University of Hull
    Not yet recruiting - verified October 2009

  • Phase IIa Study of MP4OX in Hemorrhagic Shock Patients With Lactic Acidosis

    Conditions:   Shock, Hemorrhagic;   Shock, Traumatic;   Acidosis, Lactic
    Interventions:   Drug: MP4OX;   Drug: MP4OX;   Drug: Ringer's Lactate solution
    Sponsor:   Sangart
    Not yet recruiting - verified October 2009

  • Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function

    Condition:   Advanced Solid Tumors
    Intervention:   Drug: panobinostat (LBH589)
    Sponsor:   Novartis Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Efficacy of a Prebiotic Galactooligosaccharide to Reduce Metabolic Syndrome Risk Factors in Overweight Adults

    Condition:   Metabolic Syndrome X
    Interventions:   Dietary Supplement: Bimuno;   Dietary Supplement: Maltodextrin
    Sponsors:   Clasado;   University of Reading
    Recruiting - verified October 2009

  • Evaluation of Stents to Open Restricted Airways in Patients With Centrally Placed Non-small Cell Lung Cancer

    Condition:   Non-small Cell Lung Cancer
    Interventions:   Other: Arterial puncture;   Other: Venepuncture;   Procedure: General anaesthetic;   Procedure: Inpatient stays;   Other: Walking test;   Other: Spirometry & flow volume loop assessment;   Other: Biopsy material
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified October 2009

  • Novel Prognostic Markers in Renal Cancer

    Condition:   Renal Cell Carcinoma
    Intervention:  
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified October 2009

  • A Study of the Safety and Effectiveness of Two New Malaria Vaccines

    Condition:   Malaria
    Interventions:   Biological: AdCh63-MSP1 (lower dose) vaccine and MVA-MSP1 vaccine;   Biological: AdCh63-MSP1 vaccine (higher dose) and MVA-MSP1 vaccine followed by challenge
    Sponsor:   University of Oxford
    Not yet recruiting - verified October 2009

  • Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis

    Conditions:   Psychosis;   Schizophrenia;   Bipolar Disorder;   Schizo-affective Disorder
    Intervention:   Other: Acceptance and Commitment Therapy
    Sponsors:   University of Glasgow;   Greater Glasgow and Clyde NHS
    Not yet recruiting - verified October 2009

  • The Identification of Novel Prognostic Markers in Melanoma

    Condition:   Malignant Melanoma
    Intervention:  
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified October 2009

  • SuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy)

    Condition:   Breast Cancer
    Intervention:   Radiation: Imaging investigations (with radiation)
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified October 2009

  • Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma

    Condition:   Asthma
    Intervention:   Biological: Mepolizumab (treatment) - Severe asthma
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified October 2009

  • Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT)

    Condition:   Actinic Keratosis
    Intervention:   Procedure: Metvix PDT
    Sponsor:   Galderma
    Recruiting - verified November 2009

  • Efficacy and Safety of Aclidinium Bromide at Two Dose Levels Versus Placebo Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Aclidinium bromide;   Drug: Placebo
    Sponsors:   Almirall S.A.;   Forest Laboratories
    Recruiting - verified November 2009

  • A Comparison of Insoles Used to Prevent Neuropathic Diabetic Foot Ulceration

    Conditions:   Diabetes;   Neuropathic Foot
    Intervention:   Device: Insole
    Sponsors:   University of Plymouth;   Cornwall and Illes of Scilly Primary Care Trust;   Plymouth Teaching Primary Care Trust;   Diabetes UK
    Completed - verified October 2009

  • Imaging 61CuATSM Uptake in Atherosclerotic Plaque Using PET-CT

    Condition:   Carotid Atherosclerosis
    Intervention:   Other: PET-CT with CuATSM
    Sponsors:   King's College London;   Guy's and St Thomas' NHS Foundation Trust
    Not yet recruiting - verified October 2009

  • The Tolerability and Effects of AZD8848 in Allergic Asthma Subjects Challenged With Inhaled Allergen

    Condition:   Allergic Asthma
    Interventions:   Drug: AZD8848;   Drug: Placebo
    Sponsor:   AstraZeneca
    Recruiting - verified October 2009

  • Cardiovascular Disease and the Effects of a Cross-curricular Physical Activity Intervention

    Condition:   Cardiovascular Disease
    Intervention:   Other: Activity Knowledge Circuits
    Sponsors:   University of Glamorgan;   Sports Council Wales;   University of Wales Institute Cardiff
    Completed - verified October 2009

  • LEO 27847 - A Study in Healthy Male Subjects

    Condition:   Healthy
    Intervention:   Drug: LEO 27847
    Sponsor:   LEO Pharma
    Recruiting - verified November 2009

  • Adaptive Planning in Bladder Cancer

    Condition:   Bladder Cancer
    Interventions:   Other: Adaptive-Planning Organ Localisation (A-POLO) (Planning CT scan);   Other: Cone beam CT acquisition
    Sponsors:   Royal Marsden NHS Foundation Trust;   Institute of Cancer Research, United Kingdom
    Recruiting - verified October 2009

  • Allopurinol in Chronic Heart Failure

    Conditions:   Chronic Heart Failure;   Hyperuricemia
    Interventions:   Drug: Allopurinol;   Drug: Placebo
    Sponsor:   National Heart and Lung Institute
    Completed - verified October 2009

  • An Exploration of Genetic Testing for Prostate Cancer Susceptibility

    Condition:   Prostate Cancer
    Intervention:  
    Sponsors:   Royal Marsden NHS Foundation Trust;   Institute of Cancer Research, United Kingdom
    Recruiting - verified October 2009

  • Efficacy of Once-Weekly Exenatide Versus Once or Twice Daily Insulin Detemir in Patients With Type 2 Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: exenatide once weekly;   Drug: insulin detemir
    Sponsors:   Amylin Pharmaceuticals, Inc.;   Eli Lilly and Company
    Recruiting - verified October 2009

  • Post-Authorization Safety Study of GSK Biologicals' Pandemic Influenza Vaccine (H1N1) in the United Kingdom

    Condition:   H1N1 Influenza Vaccination
    Intervention:   Other: Safety follow up
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified October 2009

  • Safety and Effectiveness on Arterial Structure and Function of ACZ885 in Atherosclerosis and Either Type 2 Diabetes Mellitus (T2DM) or Impaired Glucose Tolerance (IGT) Patients

    Conditions:   Diabetes Mellitus, Type 2;   Atherosclerosis;   Prediabetic State
    Interventions:   Drug: ACZ885 (Canakinumab);   Drug: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Not yet recruiting - verified October 2009

  • Intradialytic Progressive Resistance Training for Maintenance Haemodialysis Patients

    Condition:   Chronic Kidney Disease
    Interventions:   Other: Progressive resistance training programme;   Other: Stretching control group
    Sponsors:   Bangor University;   United Kingdom: National Health Service;   Keith Griffiths,Consultant Clinical Biochemist;   Department of Clinical Chemistry, Ysbyty Gwynedd, Bangor, Gwynedd,LL57 2PW;   Renal unit Ysbyty Gwynedd, Bangor, Gwynedd;   Renal Unit Ysbyty Glan Clwyd, Rhyl, Denbighshire;   College of Health and Behavioural Science, Bangor University, Gwynedd Wales;   NWORTH (The Bangor Trials Unit), Bangor University, Bangor, Gwynedd
    Active, not recruiting - verified November 2009

  • Educational Follow-up in a Cohort of Children at the Royal Marsden Hospital (RMH)

    Condition:   Brain Tumour
    Intervention:  
    Sponsor:   Royal Marsden NHS Foundation Trust
    Recruiting - verified October 2009

  • Differential Trough Effects of 'Triple Therapy' on Pulmonary Function in Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   COPD
    Interventions:   Drug: Budesonide/formoterol and tiotropium;   Drug: Budesonide/formoterol and placebo
    Sponsor:   University of Dundee
    Completed - verified October 2009

  • Chesterfield Micro-implant Study Involving Three Types of Anchorage Methods in Orthodontics

    Conditions:   Malocclusion;   Patients Requiring Anchorage Reinforcement;   Class II Buccal Segment Relationship
    Interventions:   Device: Extraoral anchorage;   Device: Intraoral skeletal anchorage - Temporary anchorage device;   Device: Intraoral dental anchorage
    Sponsors:   Chesterfield and North Derbyshire Royal Hospital;   Royal Derbyshire Hospital
    Enrolling by invitation - verified October 2009

  • Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma

    Condition:   Asthma
    Interventions:   Drug: Fluticasone Propionate;   Drug: Fluticasone Propionate
    Sponsor:   University of Dundee
    Not yet recruiting - verified October 2009

  • Dose-Escalation Study of PHA-793887 in Patients With Advanced/Metastatic Solid Tumors

    Condition:   Advanced/Metastatic Solid Tumors
    Intervention:   Drug: PHA-793887
    Sponsor:   Nerviano Medical Sciences
    Terminated - verified October 2009

  • Study to Assess the Efficacy and Safety of Repeated Administration of BIM 23A760 in Patients With Acromegaly

    Condition:   Acromegaly
    Intervention:   Drug: BIM 23A760
    Sponsor:   Ipsen
    Recruiting - verified November 2009

  • Study Evaluating Safety, Tolerability and Efficacy of YM150 in Subjects With Acute Coronary Syndromes

    Condition:   Acute Coronary Syndrome
    Interventions:   Drug: YM150;   Drug: Placebo
    Sponsor:   Astellas Pharma Inc
    Recruiting - verified October 2009

  • AMAP102 - Safety, Tolerability and Pharmacokinetics in Healthy Subjects

    Condition:   Healthy Volunteers
    Intervention:   Drug: AMAP102
    Sponsor:   AnaMar Medical AB
    Terminated - verified October 2009

  • Fibrinogen Versus Fresh Frozen Plasma in Major Vascular Surgery

    Condition:   Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair
    Interventions:   Biological: Fibrinogen concentrate;   Biological: Fresh Frozen Plasma
    Sponsors:   University of Edinburgh;   NHS Lothian;   CSL Behring
    Not yet recruiting - verified October 2009

  • Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure

    Conditions:   COPD;   Chest Wall Disease;   Neuromuscular Disease;   Obesity Hypoventilation
    Interventions:   Other: Pressure support ventilation;   Other: Pressure control ventilation
    Sponsor:   Guy's and St Thomas' NHS Foundation Trust
    Recruiting - verified October 2009

  • Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension

    Condition:   Resistant Hypertension
    Interventions:   Drug: Losartan and hydrochlorothiazide;   Drug: Hydrochlorothiazide switched over with Losartan at 8 weeks
    Sponsors:   University of Cambridge;   British Heart Foundation
    Not yet recruiting - verified October 2009

  • Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

    Condition:   Carcinoma, Hepatocellular
    Interventions:   Drug: BIBF 1120;   Drug: Sorafenib
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009

  • Safety, Tolerability and Pharmacokinetic Study of Multiple Doses of CS-8958

    Condition:   Influenza
    Interventions:   Drug: CS-8958;   Other: Placebo
    Sponsors:   Biota Scientific Management Pty Ltd;   National Institute of Allergy and Infectious Diseases (NIAID)
    Active, not recruiting - verified October 2009

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